Best opening game performances, 1933-2017 See All News Most Yards Rushing 250 - O.J. Simpson, Buffalo vs. New England, Sept. 16, 1973 231 - Arian Foster, Houston vs. Indianapolis, Sept. 12, 2010 220 - Michael Turner, Atlanta vs. Detroit, Sept. 7, 2008 216 - Eddie George, Tennessee vs. Oakland, Aug. 31, 1997 206 - George Rogers, New Orleans vs. St. Louis, Sept. 4, 1983 Most Yards Passing 554 - Norm Van Brocklin, L.A. Rams vs. N.Y. Yanks, Sept. 28, 1951 517 - Tom Brady, New England vs. Miami, Sept. 12, 2011 473 - Dan Marino, Miami vs. New England, Sept. 4, 1994 462 - Peyton Manning, Denver vs. Baltimore, Sept. 5, 2013 450 - Eli Manning, New York Giants vs. Dallas, Sept. 8, 2013 Most Yards Receiving 241 - Frank Clarke, Dallas vs. Washington, Sept. 16, 1962 217 - Anquan Boldin, Arizona vs Detroit, Sept. 7, 2003 212 - Hugh Taylor, Washington vs. Philadelphia, Sept. 28, 1947 211 - Lance Alworth , San Diego vs. Denver, Sept. 11, 1965 211 - Irving Fryar, Miami vs. New England, Sept. 4, 1994 Back to news